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Research article
First published online September 1, 2018

Plastic Pollution and Potential Solutions

Abstract

A review is presented of the manufacture and use of different types of plastic, and the effects of pollution by these materials on animal, human and environmental health, insofar as this is known. Since 2004, the world has made as much plastic as it did in the previous half century, and it has been reckoned that the total mass of virgin plastics ever made amounts to 8.3 billion tonnes, mainly derived from natural gas and crude oil, used as chemical feedstocks and fuel sources. Between 1950 and 2015, a total of 6.3 billion tonnes of primary and secondary (recycled) plastic waste was generated, of which around 9% has been recycled, and 12% incinerated, with the remaining 79% either being stored in landfills or having been released directly into the natural environment. In 2015, 407 million tonnes (Mt) of plastic was produced, of which 164 Mt was consumed by packaging (36% of the total). Although quoted values vary, packaging probably accounts for around one third of all plastics used, of which approximately 40% goes to landfill, while 32% escapes the collection system. It has been deduced that around 9 Mt of plastic entered the oceans in 2010, as a result of mismanaged waste, along with up to 0.5 Mt each of microplastics from washing synthetic textiles, and from the abrasion of tyres on road surfaces. However, the amount of plastics actually measured in the oceans represents less than 1% of the (at least) 150 Mt reckoned to have been released into the oceans over time. Plastic accounts for around 10% by mass of municipal waste, but up to 85% of marine debris items – most of which arrive from land-based sources. Geographically, the five heaviest plastic polluters are P.R. China, Indonesia, Philippines, Vietnam and Sri Lanka, which between them contribute 56% of global plastic waste. Larger, primary plastic items can undergo progressive fragmentation to yield a greater number of increasingly smaller ‘secondary’ microplastic particles, thus increasing the overall surface area of the plastic material, which enhances its ability to absorb, and concentrate, persistent organic pollutants (POPs) such as dichlorodiphenyltrichloroethane (DDT) and polychlorinated biphenyls (PCBs), with the potential to transfer them to the tissues of animals that ingest the microplastic particles, particularly in marine environments.
Although fears that such microparticles and their toxins may be passed via food webs to humans are not as yet substantiated, the direct ingestion of microplastics by humans via drinking water is a distinct possibility – since 92% of samples taken in the USA and 72% in Europe showed their presence – although any consequent health effects are as yet unclear. Foodstuffs may also become contaminated by microplastics from the air, although any consequent health effects are also unknown. In regard to such airborne sources, it is noteworthy that small plastic particles have been found in human lung tissue, which might prove an adverse health issue under given circumstances. It is also very striking that microplastics have been detected in mountain soils in Switzerland, which are most likely windborne in origin. Arctic ice core samples too have revealed the presence of microplastics, which were most likely carried on ocean currents from the Pacific garbage patch, and from local pollution from shipping and fishing. Thus, sea ice traps large amounts of microplastics and transports them across the Arctic Ocean, but these particles will be released into the global environment when the ice melts, particularly under the influence of a rising mean global temperature.
While there is a growing emphasis toward the substitution of petrochemically derived plastics by bioplastics, controversy has arisen in regard to how biodegradable the latter actually are in the open environment, and they presently only account for 0.5% of the total mass of plastics manufactured globally. Since the majority of bioplastics are made from sugar and starch materials, to expand their use significantly raises the prospect of competition between growing crops to supply food or plastics, similarly to the diversion of food crops for the manufacture of primary biofuels. The use of oxo-plastics, which contain additives that assist the material to degrade, is also a matter of concern, since it is claimed that they merely fragment and add to the environmental burden of microplastics; hence, the European Union has moved to restrict their use.
Since 6% of the current global oil (including natural gas liquids, NGLs) production is used to manufacture plastic commodities – predicted to rise to 20% by 2050 – the current approaches for the manufacture and use of plastics (including their end-use) demand immediate revision. More extensive collection and recycling of plastic items at the end of their life, for re-use in new production, to offset the use of virgin plastic, is a critical aspect both for reducing the amount of plastic waste entering the environment, and in improving the efficiency of fossil resource use. This is central to the ideology underpinning the circular economy, which has common elements with permaculture, the latter being a regenerative design system based on ‘nature as teacher’, which could help optimise the use of resources in town and city environments, while minimising and repurposing ‘waste’. Thus, food might be produced more on the local than the global scale, with smaller inputs of fuels (including transportation fuels for importing and distributing food), water and fertilisers, and with a marked reduction in the use of plastic packaging. Such an approach, adopted by billions of individuals, could prove of immense significance in ensuring future food security, and in reducing waste and pollution – of all kinds.

12. References

1. Wikiquote (2018) The Graduate. https://en.wikiquote.org/wiki/The_Graduate [accessed 17 May 2018].
2. Geyer R., Jambeck J.R., and Law K.L. (2017) Sci. Adv., 3, e1700782.
3. Wikipedia (2018) Thermoplastic. https://en.wikipedia.org/wiki/Thermoplastic [accessed 17 May 2018].
4. Wikipedia (2018) Thermosetting polymer. https://en.wikipedia.org/wiki/Thermosetting_polymer [accessed 17 May 2018].
5. Fenichell S. (1996) Plastic: the making of a synthetic century. HarperBusiness, New York.
6. UK Patent Office (1865) Patents for inventions [ebook], p. 255. ReInk Books. https://books.google.co.uk/books?id=0nCoU-2tAx8C&pg=PA255&redir_esc=y#v=onepage&q&f=false [accessed 17 May 2018].
7. Vitale T. (2009) History, science and storage of acetate film base. http://videopreservation.conservation-us.org/library/history_science_storage_of_acetate_base_film_16b.pdf [accessed 18 May 2018].
8. Baumann E. (1872) Ann. Chem. Phar., 163, 308–322.
9. Von Pechmann H. (1898) Ber. Dtsch. Chem. Ges., 31, 2640–2646.
10. Wikipedia (2018) Bakelite. https://en.wikipedia.org/wiki/Bakelite [accessed 17 May 2018].
11. Wikipedia (2018) Timeline of plastic development. https://en.wikipedia.org/wiki/Timeline_of_plastic_development [accessed 17 May 2018].
12. Staudinger H. (1953) Macromolecular chemistry. https://www.nobelprize.org/nobel_prizes/chemistry/laureates/1953/staudinger-lecture.pdf [accessed 17 May 2018].
13. Staudinger H. (1920) Ber. Dtsch. Chem. Ges., 53, 1073–1085.
14. Mülhaupt R. (2004) Angew. Chem. Int. Ed., 43, 1054–1063.
15. Morawetz H. (1995) Macromol. Symp., 98, 1173–1184.
16. Paul H.C., and Lodge P.T. (2007) Polymer chemistry, second ed., pp. 336, 338–339. Boca Raton, CRC.
17. Smith J.K., and Hounshell D.A. (1985) Science, 229, 436–442.
18. Staudinger H., Heuer W., Husemann E., and Rabinovitch I.J. (1936) Trans. Faraday Soc., 32, 323–335.
19. Columbia Electronic Encyclopedia (2012) Plastic. https://www.infoplease.com/encyclopedia/science-and-technology/chemistry/organic-chemistry/plastic [accessed 18 May 2018].
20. Wikipedia (2018) Plastics. https://en.wikipedia.org/wiki/Plastic#Common_plastics [accessed 18 May 2018].
22. Rhodes C.J. (2016) Sci. Prog., 99, 97–104.
23. Political Economist (2016) World energy 2016–2050: annual report. http://peakoilbarrel.com/world-energy-2016-2050-annual-report/ [accessed 18 May 2018].
24. Tullo A.H. (2016) Chem. Eng. News, 94, 32–37.
25. Rhodes C.J. (2017) Sci. Prog., 100, 80–129.
26. Natural Resources Defense Council (2013) Food facts. https://www.nutrition.va.gov/docs/Sustainability/foodwaste_2pgr.pdf [accessed 18 May 2018].
27. Hammer J., Kraak M.H., and Parsons J.R. (2012) Rev. Environ. Contam. Toxicol., 220, 1–44.
28. Mattsson K., Hansson L.-A., and Cedervall T. (2015) Environ. Sci. Process. Impact., 17, 1712–1721.
29. Rhodes C.J. (2011) Sci. Prog., 94, 339–413.
30. Rhodes C.J. (2012) Sci. Prog., 95, 345–446.
31. Rochman C.M., Kross S.M., Armstrong J.B. et al. (2015) Environ. Sci. Technol., 49, 10759–10761.
32. Driedger A.G.J., Dürr H.H., Mitchell K., and Van Cappellen P. (2015) J. Great Lakes Res., 41, 9–19.
33. National Ocean Service (2018) What are microplastics? https://oceanservice.noaa.gov/facts/microplastics.html [accessed 20 May 2018].
34. Cole M., Lindeque P., Halsband C., and Galloway T.S. (2011) Mar. Pollut. Bull., 62, 2588–2597.
35. Browne M.A., Crump P., Niven S.J. et al. (2011) Environ. Sci. Technol., 45, 9175–9179.
36. GESAMP (2015) Sources, fate and effects of microplastics in the marine environment: a global assessment, p. 96. International Maritime Organization, London. http://ec.europa.eu/environment/marine/good-environmental-status/descriptor-10/pdf/GESAMP_microplastics%20full%20study.pdf [accessed 20 May 2018].
37. The Pacific Protection Initiative (2007) AB258: Nurdles. https://web.archive.org/web/20080420095307/ http://healthebay.org/currentissues/ppi/bills_AB258.asp [accessed 20 May 2018].
38. Rehse S., Kloas W., and Zarfl C. (2018) Int. J. Environ. Res. Public Health, 15, 280.
39. Faure F., Demars C., Wieser O. et al. (2015) Environ. Chem., 12, 582–591.
40. Yonkos L.T., Friedel E.A., Perez-Reyes A.C. et al. (2014) Environ. Sci. Technol., 48, 14195–14202.
41. McCormick A.R., Hoellein T.J., London M.G. et al. (2016) Ecosphere, 7, e01556.
42. Lebreton L.C.M., van der Zwet J., Damsteeg J.-W. et al. (2017) Nat. Commun., 8, 15611.
43. Zhao S., Zhu L., Wang T., and Li D. (2014) Mar. Pollut. Bull., 86, 562–568.
44. Lozano R.L., and Mouat J. (2009) Marine litter in the North-East Atlantic region: assessment and priorities for response. OSPAR Commission, London, UK. https://qsr2010.ospar.org/media/assessments/p00386_Marine_Litter_in_the_North-East_Atlantic_with_addendum.pdf [accessed 20 May 2018].
45. Koelmans A.A., Bakir A., Burton G.A., and Janssen C.R. (2016) Environ. Sci. Technol., 50, 3315–3326.
46. Lohmann R. (2017) Integr. Environ. Assess. Manag., 13, 460–465.
47. Ziccardi L.M., Edgington A., Hentz K. et al. (2016) Environ. Toxicol. Chem., 35, 1667–1676.
48. Kleinteich J., Seidensticker S., Marggrander N., and Zarfl C. (2018) Int. J. Environ. Res. Public Health, 15, 287.
49. Mato Y. (2001) Environ. Sci. Technol., 35, 318–324.
50. Andrady A.L. (2011) Mar. Pollut. Bull., 62, 1596–1605.
51. Eriksen M., Lebreton L.C.M., Carson H.S. et al. (2014) PLoS ONE, 9, e111913.
52. Reisser J., Shaw J., Wilcox C. et al. (2013) PLoS ONE, 8, e80466.
53. Cózar A., Echevarría F., González-Gordillo J.I. et al. (2014) PNAS, 111, 10239–10244.
54. Browne M.A. (2015) Sources and pathways of microplastics to habitats. In: Bergmann M., Gutow L., and Klages M. (eds), Marine anthropogenic litter, pp. 229–244. Springer, Cham.
55. Galloway T.G. (2015) Micro- and nano-plastics and human health. In: Bergmann M., Gutow L., and Klages M. (eds), Marine anthropogenic litter, pp. 343–366. Springer, Cham.
56. Alexander J., Barregard L., Bignami M. et al. (2016) EFSA Journal, 14, 4501. https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa.2016.4501 [accessed 21 May 2018].
57. Thompson R.C., Olsen Y., Mitchell R.P. et al. (2004) Science, 304, 838.
59. Woodall L.C., Sanchez-Vidal A., Canals M. et al. (2014) R. Soc. Open Sci., 1, 140317.
60. Lassen C., Hansen S.F., Magnusson K. et al. (2015) Microplastics: occurrence, effects and sources of releases to the environment in Denmark, p. 14. Ministry of Environment and Food in Denmark, Danish Environmental Protection Agency, Copenhagen. https://www2.mst.dk/Udgiv/publications/2015/10/978-87-93352-80-3.pdf [accessed 21 May 2018].
61. Boucher J., and Friot D. (2017) Primary microplastics in the oceans: a global evaluation of sources. IUCN, Gland, Switzerland. https://portals.iucn.org/library/sites/library/files/documents/2017-002.pdf [accessed 21 May 2018].
62. Jambeck J.R., Geyer R., Wilcox C. et al. (2015) Science, 347, 768–771.
63. Kole P.J., Löhr A.J., Van Belleghem F.G.A.J., and Ragas A.M.J. (2017) Int. J. Environ. Res. Public Health, 14, 1265.
64. Tyree C., and Morrison D. (2017) Invisibles – the plastic inside us. https://orbmedia.org/stories/Invisibles_plastics/multimedia [accessed 21 May 2018].
65. Timmers V.R.J.H., and Achten P.A.J. (2016) Atmos. Environ., 134, 10–17.
66. Carr S.A., Liu J., and Tesoro A.G. (2016) Water Res., 91, 174–182.
67. Murphy F., Ewins C., Carbonnier F., and Quinn B. (2016) Environ. Sci. Technol., 50, 5800–5808.
68. Rochman C.M., Kross S.M., Armstrong J.B. et al. (2015) Environ. Sci. Technol., 49, 10759–10761.
69. Talvitie J., Mikola A., Koistinen A., and Setala O. (2017) Water Res., 123, 401–407.
70. Wright S.L., Rowe D., Thompson R.C., and Galloway T.S. (2013) Curr. Biol., 23, 1031–1033.
71. Chae Y., and An Y.-J. (2017) Mar. Pollut. Bull., 124, 624–632.
72. Wright S.L., Thompson R.C., and Galloway T.S. (2013) Environ. Pollut., 178, 483–492.
73. Lönnstedt O.M., and Eklöv P. (2016) Science, 352, 1213–1216.
74. Berg J. (2017) Science, 358, 1549.
75. Cole M., Lindeque P., Fileman E. et al. (2013) Environ. Sci. Technol., 47, 6646–6655.
76. Savoca M.S., Wohlfeil M.E., Ebeler S.E., and Nevitt G.A. (2016) Sci. Adv., 2, e1600395.
77. Chiras D.D. (2004) Environmental science: creating a sustainable future. Jones & Bartlett Learning, Burlington, Massachusetts.
78. Reichert J., Schellenberg J., Schubert P., and Wilke T. (2018) Environ. Pollut., 237, 955–960
79. Davison P., and Asch R.G. (2011) Mar. Ecol. Prog. Ser., 432, 173–180.
80. Wieczorek A.M., Morrison L., Croot P.L. et al. (2018) Front. Mar. Sci., 5, 39.
81. Jamieson A.J., Malkocs T., Piertney S.B. et al. (2017) Nature Ecol. Evol., 1, 0051.
82. Newcastle University Press Office (2017) Man-made fibres and plastic found in the deepest living organisms. https://www.ncl.ac.uk/press/articles/archive/2017/11/plasticocean/ [accessed 21 May 2018].
83. Hill M.K. (1997) Understanding environmental pollution, p. 257. Cambridge University Press, Cambridge.
84. Rodríguez A., Rodríguez B., and Nazaret Carrasco M. (2012) Mar. Pollut. Bull., 64, 2219–2223.
85. Mathieu-Denoncourt J., Wallace S.J., de Solla S.R., and Langlois V.S. (2015) Gen. Compar. Endocrinol., 219, 74–88.
86. Le Guern C. (2018) When the mermaids cry: the great plastic tide. http://plastic-pollution.org/ [accessed 22 May 2018].
87. Wilcox C., Van Sebille E., and Hardesty B.D. (2015) PNAS, 112, 11899–11904.
88. North E.J., and Halden R.U. (2013) Rev. Environ. Health, 28, 1–8.
89. Environmental and Occupational Health (2003) PubH 5103: exposure to enviromental hazards. Phthalates. http://enhs.umn.edu/current/5103/phth/toxicity.html [accessed 22 May 2018].
90. World Health Organization (2018) Nutrition. 3.5. Availability and consumption of fish. http://www.who.int/nutrition/topics/3_foodconsumption/en/index5.html [accessed 22 May 2018].
91. Nelms S.E., Galloway T.S., Godley B.J. et al. (2018) Environ. Pollut., 239, 999–1007.
92. Lwanga E.H., Vega J.M., Quei V.K. et al. (2017) Sci. Rep., 7, 14071.
93. Kosuth M., Wattenberg E.V., Mason S.A. et al. (2017) Synthetic polymer contamination in global drinking water. https://orbmedia.org/stories/Invisibles_final_report [accessed 22 May 2018].
94. Wright S.L., and Kelly F.J. (2017) Environ. Sci. Technol., 51, 6634–6647.
95. Li J., Yang D., Li L., Jabeen K., and Shi H. (2015) Environ. Pollut., 207, 190–195.
96. Mathalon A., and Hill P. (2014) Mar. Pollut. Bull., 81, 69–79.
97. Van Cauwenberghe L., and Janssen C.R. (2014) Environ. Pollut., 193, 65–70.
98. Liebezeit G., and Liebezeit E. (2013) Food Addit. Contam. Part A, 30, 2136–2140.
99. Liebezeit G., and Liebezeit E. (2014) Food Addit. Contam. Part A, 31, 1574–1578.
100. Yang D., Shi H., Li L. et al. (2015) Environ. Sci. Technol., 49, 13622–13627.
101. Dris R., Gasperi J., Rocher V. et al. (2015) Envir. Chem., 12, 592–599.
102. Dris R., Gasperi J., Saad M. et al. (2016) Mar. Pollut. Bull., 104, 290–293.
103. Catarino A.I., Macchia V., Sanderson W.V. et al. (2018) Environ. Pollut., 237, 675–684.
104. Zubris K.A.V., and Richards B.K. (2005) Environ. Pollut., 138, 201–211.
105. Bouwmeester H., Hollman P.C.H., and Peters R.J.B. (2015) Environ. Sci. Technol., 49, 8932–8947.
106. Warheit D.B., Hart G.A., Hesterberg T.W. et al. (2001) Crit. Rev. Toxicol., 31, 697–736.
107. Pauly J.L., Stegmeier S.J., Allaart H.A. et al. (1998) Cancer Epidemol. Biomark. Prev., 7, 419–428.
108. Gregory M.R. (2009) Phil. Trans. R. Soc. B, 364, 2013–2025.
109. Barnes D.K.A., Galgani F., Thompson R.C., and Barlaz M. (2009) Phil. Trans. R. Soc. B, 364, 1985–1998.
110. Wikipedia (2018) Autotroph. https://en.wikipedia.org/wiki/Autotroph [accessed 22 May 2018].
111. Yokota K., Waterfield H., Hastings C. et al. (2017) Liminol. Oceanog. Lett., 2, 91–104.
112. Webb H.K., Arnott J., Crawford R.J., and Ivanova E.P. (2013) Polymers, 5, 1–18.
113. Raquez J.-M., Bourgeois A., Jacobs H. et al. (2011) J. Appl. Polym. Sci., 122, 489–496.
114. Zheng Y., Yanful E.K., and Bassi A.S. (2005) Crit. Rev. Biotechnol., 25, 243–250.
115. Yamada-Onodera K., Mukumoto H., Katsuyaya Y. et al. (2001) Polym. Degrad. Stabil., 72, 323–327.
116. Zhang J., Wang X., Gong J., and Gu Z. (2004) J. Appl. Polym. Sci., 93, 1089–1096.
117. Xu S.-Y., Zhang H., He P.-J., and Shao L.-M. (2011) Environ. Technol., 32, 1269–1277.
118. Svenson A., Sjöholm S., Allard A.-S., and Kaj L. (2009) Environ. Toxicol., 26, 233–239.
119. Tsuchida D., Kajihara Y., Shimidzu N. et al. (2011) Waste Manag. Res., 29, 594–601.
120. Mouat J., Lozano R.P., and Bateson H. (2010) Economic impacts of marine litter. http://www.kimointernational.org/wp/wp-content/uploads/2017/09/KIMO_Economic-Impacts-of-Marine-Litter.pdf [accessed 22 May 2018].
121. European Commission (2018) Environment. Our oceans, seas and coasts. Descriptor 10: marine litter. http://ec.europa.eu/environment/marine/good-environmental-status/descriptor-10/index_en.htm [accessed 22 May 2018].
122. Thompson R.C., Swan S.H., Moore C.J., and vom Saal F.S. (2009) Phil. Trans. R. Soc. B, 364, 1969–2166
123. Thompson R.C., Moore C.J., vom Saal F.S., and Swan S.H. (2009) Phil. Trans. R. Soc. B, 364, 2153–2166.
124. Sherrington C., Darrah C., Hann A. et al. (2016) Study to support the development of measures to combat a range of marine litter sources. Report for European Commission DG Environment. http://mcc.jrc.ec.europa.eu/documents/201606243248.pdf [accessed 22 May 2018].
125. Beachwatch (2009) Beachwatch big weekend. https://www.mcsuk.org/downloads/pollution/beachwatch/Summary%20report_2009_e-mail.pdf [accessed 22 May 2018].
126. Van Sebille E., Wilcox C., Lebreton L. et al. (2015) Environ. Res. Lett., 10, 124006.
127. Dawson A.L., Kawaguchi S., King C.K. et al. (2018) Nature Comm., 9, 1001.
128. Goldstein M., and Goodwyn D. (2013) Peer J., 184, 2–17.
129. Jantz L., Morishige C., Bruland G., and Lepczyk C. (2013) Mar. Poll. Bull., 69, 97–104.
130. Lusher A., McHugh M., and Thompson R. (2013) Mar. Poll. Bull., 67, 94–99.
131. Zettler E., Mincer T., and Amaral-Zettler L. (2013) Environ. Sci. Technol., 47, 7137–7146.
132. Harshvardhan K., and Jha B. (2013) Mar. Poll. Bull., 77, 100–106.
133. Balasubramanian V., Natarajan K., Hemambika B. et al. (2010) Appl. Microbiol., 51, 205–211.
134. Bakir A., Rowland S., and Thompson R. (2014) Environ. Pollut., 185, 16–23.
135. Setälä O., Fleming-Lehtinen V., and Lehtiniemi M. (2014) Environ Pollut., 185, 77–83.
136. Farrell P., and Nelson K. (2013) Environ. Pollut., 177, 1–3.
137. Stephens B.B., Gurney K.R., Tans P.P. et al., (2007) Science, 316, 1732–1735.
138. Day R.H., Shaw D.G., and Ignell S.E. (1988) The quantitative distribution and characteristics of neuston plastic in the North Pacific Ocean, 1985–88. In: Shomura R.S., and Godfrey M.L. (eds), Proceedings of the Second International Conference on Marine Debris, Honolulu, Hawaii, 2–7 April 1989. https://swfsc.noaa.gov/publications/TM/SWFSC/NOAA-TM-NMFS-SWFSC-154_P247.PDF [accessed 23 May 2018].
139. Lebreton L., Slat B., Ferrari F. et al. (2018) Sci. Rep., 8, 4666.
140. Debroas D., Mone A., and Ter Halle A. (2017) Sci. Tot. Environ., 599–600, 1222–1232.
141. Lavers J.F., and Bond A.L. (2017) PNAS, 114, 6052–6055.
143. Eriksen M., Mason S., Wilson S. et al. (2013) Mar. Pollut. Bull., 77, 177–182.
144. Baldwin A.K., Corsi S.R., and Mason S.A. (2016) Environ. Sci. Technol., 50, 10377–10385.
145. Ballent A., Corcoran P.L., Madden O. et al. (2016) Mar. Pollut. Bull., 110, 383–395.
146. Small C., and Nicholls R.J. (2003) J. Coastal Res., 19, 584–599.
147. Schmidt C., Krauth T., and Wagner S. (2017) Environ. Sci. Technol., 51, 12246–12253.
148. Schmidt C., Krauth T., and Wagner S. (2018) Environ. Sci. Technol., 52, 927–927.
149. Bawden T. (2017) inews. 11 October. https://inews.co.uk/news/environment/95-ocean-plastic-delivered-just-10-rivers/ [accessed 24 May 2018].
150. Scheurer M., and Bigalke M. (2018) Environ. Sci. Technol., 52, 3591–3598.
151. Huerta Lwanga E., Gertsen H., Gooren H. et al. (2016) Environ. Sci. Technol., 50, 2685–2691.
152. Cao D., Wang X., Luo X. et al. (2017) IOP Conf. Ser. Earth Environ. Sci., 61, 012148.
153. Rodriguez-Seijo A., Lourenco J., Rocha-Santos T.A.P. et al. (2017) Environ. Pollut., 220, 495–503.
154. Peeken I., Primpke S., Beyer B. et al. (2017) Nature Comm., 9, 1505.
155. Obbard R.W., Sadri S., Wong Y.Q. et al. (2014) Earth's Future, 2, 315–320.
156. European Commission (2018) Commission Regulation (EU) 2018/213 of 12 February 2018 on the use of bisphenol A in varnishes and coatings intended to come into contact with food and amending Regulation (EU) No 10/2011 as regards the use of that substance in plastic food contact materials. http://eur-lex.europa.eu/legal-content/EN/TXT/?uri=uriserv:OJ.L_.2018.041.01.0006.01.ENG&toc=OJ:L:2018:041:TOC [accessed 25 May 2018].
157. Federal Register (2012) Indirect food additives: polymers. https://www.federalregister.gov/documents/2012/07/17/2012-17366/indirect-food-additives-polymers#p-3 [accessed 25 May 2018].
158. National Toxicology Programme (2018) Bisphenol A. https://ntp.niehs.nih.gov/results/areas/bpa/clarity_bpa/clarity-bpa-program.html [accessed 25 May 2018].
159. US Food and Drug Administration (2018) Statement from Stephen Ostroff M.D., Deputy Commissioner for Foods and Veterinary Medicine, on National Toxicology Program draft report on Bisphenol A. https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm598100.htm [accessed 25 May 2018].
160. Abbasi J. (2018) JAMA, 319, 1644–1646. https://jamanetwork.com/journals/jama/article-abstract/2675909?redirect=true [accessed 2 May 2018].
161. Mesnage R., Phedonos A., Arno M. et al. (2017) Toxicol. Sci., 158, 431–443.
162. Byrne D. (2011) Official journal of the European communities, L315/45-49. https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:31999D0815&from=EN [accessed 25 May 2018].
163. The European Commision (1999) Official journal of the European communities, L44/2-6. https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32011R0143&from=EN [accessed 25 May 2018].
164. ChemicalWatch (2018) EU notifies WTO of proposed phthalates restriction in toys. https://chemicalwatch.com/65673/eu-notifies-wto-of-proposed-phthalates-restriction-in-toys [accessed 25 May 2018].
165. Eriksen B.E. (2017) Chem. Eng. News, 95, 15.
166. American Chemistry Council (2018) Phthalates. https://phthalates.americanchemistry.com/Industry/Toys/ [accessed 25 May 2018].
167. Bureau Veritas CPS (2017) CPSC publishes final rule on the ban of certain phthalates in toys and child care articles. http://www.bureauveritas.com/home/about-us/our-business/cps/whats-new/bulletins/cpsc+bans+certain+phthalates+in+toys+and+child+care+articles [accessed 25 May 2018].
168. Beat the Microbead (2018) Beat the microbead. http://www.beatthemicrobead.org/ [accessed 25 May 2018].
170. Buxton L. (2018) Chemical Watch. 17 January. https://chemicalwatch.com/63198/eu-prepares-comprehensive-microplastics-restriction [accessed 25 May 2018].
171. European Commission (2018) EU plastics strategy. http://ec.europa.eu/environment/waste/plastic_waste.htm [accessed 25 May 2018].
172. European Commission (2018) Circular economy package. http://ec.europa.eu/environment/circular-economy/index_en.htm [accessed 25 May 2018].
173. European Commission (2015) Closing the loop – an EU action plan for the circular economy. https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A52015DC0614 [accessed 25 May 2018].
174. Carrington D. (2018) The Guardian. 9 January. https://www.theguardian.com/environment/2018/jan/09/plastic-microbeads-ban-enters-force-in-uk [accessed 25 May 2018].
175. Wikipedia (2018) Microbead. https://en.wikipedia.org/wiki/Microbead#States [accessed 25 May 2018].
176. US Congress (2015) Microbead-free waters act of 2015. H.R. 1321 (114th). https://www.govtrack.us/congress/bills/114/hr1321 [accessed 25 May 2018].
177. LEGO (2018) First sustainable LEGO® bricks will be launched in 2018. https://www.lego.com/en-us/aboutus/news-room/2018/march/pfp [accessed 25 May 2018].
179. Ma Y. (2018) Sci. Prog., 101, 1–7.
180. Transition Town Reading (2018) Refill Reading. http://www.transitionreading.org.uk/refillreading/ [accessed 25 May 2018].
182. McGlade C., and Ekins P. (2015) Nature, 517, 187–190.
183. Wikipedia (2018) Plastic pollution. https://en.wikipedia.org/wiki/Plastic_pollution [accessed 25 May 2018].
185. Garcia J.M., and Robertson M.L. (2017) Science, 358, 870–872.
187. Rahimi A., and García J.M. (2017) Nat. Chem. Rev., 1, 0046.
189. International Energy Agency (2017) Key world energy statistics. https://www.iea.org/publications/freepublications/publication/KeyWorld2017.pdf [accessed 25 May 2018].
190. EPA (2015) Plastics. www3.epa.gov/epawaste/conserve/tools/warm/pdfs/Plastics.pdf [accessed 25 May 2018].
191. Aguado R., Olazar M., San José M.J., and Bilbao J. (2002) Energy Fuels, 16, 1429.
192. Jia X., Qin C., Friedberger T. et al. (2016) Sci. Adv., 2, e1501591.
193. Jian-Bo Z., Watson E.M., Tang J., and Chen E.Y.-X., et al. (2018) Science, 360, 398–403.
195. Zhu J., Birgisson B., and Kringos N. (2014) Eur. Polym. J., 54, 18–38.
196. MacRebur® Ltd (2017) http://www.macrebur.com/ [accessed 25 May 2018].
197. Naskar M., Chaki T.K., and Reddy K.S. (2010) Thermochim. Acta, 509, 128–134.
198. Ellen MacArthur Foundation (2017) https://www.ellenmacarthurfoundation.org/ [accessed 25 May 2018].
199. Ellen MacArthur Foundation (2018) UK Plastics Pact launched by the Ellen MacArthur Foundation and WRAP. https://www.ellenmacarthurfoundation.org/news/uk-plastics-pact-launched-by-the-ellen-macarthur-foundation-and-wrap [accessed 25 May 2018].
200. European Commission (2018) A European strategy for plastics in a circular economy. http://eur-lex.europa.eu/legal-content/EN/TXT/?qid=1516265440535&uri=COM:2018:28:FIN [accessed 25 May 2018].
201. Wierckx N., Narancic T., Eberlein C. et al. (2018) Plastic biodegradation: challenges and opportunities. In: Steffan R. (ed.), Consequences of microbial interactions with hydrocarbons, oils, and lipids: biodegradation and bioremediation. Handbook of hydrocarbon and lipid microbiology, pp. 1–29. Springer, Cham, Switzerland.
202. Yoshida S., Hiraga K., Takehana T. et al. (2016) Science, 351, 1196–1199.
203. Austin H.P., Allen M.D., Donohoe B.S. et al. (2018) PNAS, 115, E4350–E435. http://www.pnas.org/content/pnas/early/2018/04/16/1718804115.full.pdf [accessed 25 May 2018].
204. Ellen MacArthur Foundation (2017) Ellen MacArthur Foundation (2017) Oxo-degradable plastic packaging is not a solution to plastic pollution, and does not fit in a circular economy. https://www.nvc.nl/userfiles/files/Ellen_MacArthur_Foundation_oxo-statement-vF.pdf [accessed 28 June 2018].
205. CommonWealth (2018) Upgrade the plastic to save the environment! http://www.cweic.org/upgrade-plastic-save-environment/ [accessed 25 May 2018].
206. Oxo-degradable Plastics Association (2017) OPA responds to MacArthur report http://www.symphonyenvironmental.com/opa-responds-macarthur-report/ [accessed 25 May 2018].
207. European Commission (2018) Report on the impact of the use of oxo degradable plastic, including oxo-degradable plastic carrier bags, on the environment. http://ec.europa.eu/environment/circular-economy/pdf/oxo-plastics.pdf [accessed 26 May 2018].
208. European Commission (2018) A European strategy for plastics in a circular economy. http://ec.europa.eu/environment/circular-economy/pdf/plastics-strategy.pdf [accessed 26 May 2018].
209. Oxo-degradable Plastics Association (2018) OPA responds to MacArthur report. http://www.biodeg.org/OPA%20responds%20to%20European%20Commission%20%20-%20%20%2019%20January%202018.pdf [accessed 26 May 2018].
210. European Bioplastics (2017) Bioplastics market data 2017. http://docs.european-bioplastics.org/publications/market_data/2017/Report_Bioplastics_Market_Data_2017.pdf [accessed 26 May 2018].
211. Selke S., Auras R., Nguyen T.A. et al. (2015) Environ. Sci. Technol., 49, 3769–3777.
212. Allen D. (2017) Legal Reader. 24 August. https://www.legalreader.com/cassava-bags-green/ [accessed 26 May 2018].
213. Wikipedia (2018) Six pack rings. https://en.wikipedia.org/wiki/Six_pack_rings [accessed 26 May 2018].
215. Wikipedia (2018) Garbage patch state. https://en.wikipedia.org/wiki/Garbage_Patch_State [accessed 26 May 2018].
217. Phantasm 57 (2018) Blue Planet II plastic pollution awareness 2018 [video]. https://www.youtube.com/watch?v=xLx4fVsYdTI [accessed 26 May 2018].
218. The Holy Father, Francis (2015) Libreria Editrice Vaticana. 24 May. http://w2.vatican.va/content/francesco/en/encyclicals/documents/papa-francesco_20150524_enciclica-laudato-si.html [accessed 26 May 2018].
219. Editorial (2015) Nature, 522, 391.
220. Jahnke A., Arp H.P.H., Escher B.I. et al. (2017) Environ. Sci. Technol. Lett., 4, 85–90.
221. Rhodes C.J. (2018) Sci. Prog., 101, 121–160.
222. Ma Y. (2018) Sci. Prog., 101, 161–170.
223. Andrady A.L., and Neal M.A. (2009) Phil. Trans. R. Soc. B, 364, 1977–1984.